from pubmed: horse by Toscan G, Cezar AS, Pereira RC, Silva GB, Sangioni LA, Oliveira LS, Vogel FS
Comparative performance of macrocyclic lactones against large strongyles in horses.
Parasitol Int. 2012 May 8;
Authors: Toscan G, Cezar AS, Pereira RC, Silva GB, Sangioni LA, Oliveira LS, Vogel FS
Several formulations of macrocyclic lactones (abamectin, ivermectin, moxidectin), including ivermectin combined with pyrantel (tetrahydropyrimidine) and ivermectin combined with praziquantel (pyrazinoisoquinolin derivative), were tested regarding their efficacy to control gastrointestinal nematodes of horses on a stud farm in southern Brazil. In addition, we tested a pharmaceutically produced generic paste containing ivermectin 4%. Similar formulations of avermectins had different efficacies measured by reduction of EPG. Levels of efficacy of the tested drugs varied against Strongylus edentatus, S. equinus and S. vulgaris. The generic paste (ivermectin 4%) was less effective than the conventional drugs.
PMID: 22580448 [PubMed – as supplied by publisher
Comment: Brand name dewormers are recommended over generic, inexpensive versions. This study illustrates the potential outcome and difference between these two formulations.