Associations of health status and conformation with longevity and lifetime competition performance in young Swedish Warmblood riding horses: 8,238 cases ( 1983-2005)

Abstract
Journal of the American Veterinary Medical Association
June 15, 2014, Vol. 244, No. 12, Pages 1449-1461

Lina Jönsson, PhD; Agneta Egenvall, DVM, PhD; Lars Roepstorff, DVM

Design—Cohort study and genetic analysis.

Animals—8,238 horses.

Procedures—Horses were examined for health, conformation, and performance from 1983 to 2005, when they were 4 to 5 years old, and competition results from 1983 to 2012 were evaluated. Associations between conformation, health, and talent scores of young horses and longevity (years in competition) and lifetime performance were analyzed. Odds ratios of competing later in life among horses with joint flexion test reactions were determined. Genetic correlations between young horse health, conformation, and talent scores and longevity and lifetime performance were determined.

Results—Good overall 4- to 5-year-old health, conformation, and talent scores for performance were phenotypically and genetically associated with greater longevity and lifetime performance. Good health was genetically correlated (rg = 0.3) to longevity and lifetime performance. Among conformation traits, body type and movements in the trot were most strongly associated with future longevity; these were genetically correlated (rg = 0.2 to 0.3) to longevity and lifetime performance. Intermediate-sized horses were associated with highest longevity and lifetime performance. Positive flexion test results were associated with lower ORs (OR, 0.59 for moderate to severe and 0.76 for minor reactions) of competing later in life, compared with no reaction, and were associated with lower longevity (0.4 years).

Conclusions and Clinical Relevance—Horses with good health and conformation at a young age had better longevity in competitions than the mean. Positive correlations suggested that improvement of health and conformation of young horses will enhance their future athletic talent and performance.

Effects of intrabursal administration of botulinum toxin type B on lameness in horses with degenerative injury to the podotrochlear apparatus

Santiago D. Gutierrez-Nibeyro, DVM, MS; Marcos P. Santos, DVM.

Objective—To determine the safety and short-term efficacy of intrabursal administration of botulinum toxin type B (BTXB) to alleviate lameness in horses with degenerative injury to the podotrochlear apparatus (PA).

Animals—10 Quarter Horses with degenerative injury to the PA.

Procedures—Degenerative injury to the PA was confirmed with diagnostic analgesia and imaging. Then, BTXB (3.8 to 4.5 U/kg) was injected into the podotrochlear (navicular) bursa of each horse. Three horses were used in a safety evaluation. Subsequently, video recordings of lameness evaluations were obtained for 7 client-owned horses 5 days before (baseline) and 7 and 14 days after BTXB treatment and used to determine the effect of BTXB injection on lameness; 1 horse was removed from the study 8 days after BTXB treatment. Three investigators who were unaware of the treated forelimbs or time points separately reviewed the recordings and graded the lameness of both forelimbs of the horses.

Results—Improvement in lameness of the treated forelimbs was detected at 1 or both time points after BTXB administration in all horses. However, all horses had some degree of lameness at the end of the study. Two horses developed transient increases in lameness 48 to 72 hours after treatment; lameness resolved uneventfully.

Conclusions and Clinical Relevance—Intrabursal injection of BTXB temporarily alleviated chronic lameness in horses with degenerative injury to the PA, without causing serious short-term adverse effects. Further investigation into the potential use of BTXB in horses affected by degenerative injury to the PA is warranted.

Evaluation of the safety of a combination of oral administration of phenylbutazone and firocoxib in horses.

Evaluation of the safety of a combination of oral administration of phenylbutazone and firocoxib in horses.

J Vet Pharmacol Ther. 2013 Dec 20;

Authors: Kivett L, Taintor J, Wright J

Abstract
Simultaneous administration of a nonselective COX inhibitor and a COX-2 specific NSAID has not been previously reported in horses. The goal of this study was to determine the safety of a 10-day dosage regimen of phenylbutazone and firocoxib, both at their standard dosages, in horses. Six horses were administered 2.2 mg/kg of phenylbutazone and 0.1 mg/kg of firocoxib by mouth, daily for 10 days. Horses were assessed daily for changes in behavior, appetite, fecal consistency, signs of abdominal pain, and oral mucous membrane ulceration. Horses were assessed prior to and on the last day of treatment for changes in serum creatinine, albumin, total protein, and urine-specific gravity. Horses underwent endoscopic examination of the esophagus, stomach, and pylorus prior to and 24 hours after the last treatment. A significant change in serum creatinine and total protein was observed on day 10 of treatment. No other significant findings were noted during the experiment. Results indicated that co-administration of phenylbutazone and firocoxib may cause renal disease.
PMID: 24354928

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racing horoughbred Racehorse Fatal Injury Rate Steady in 2012

    According to a March 8 Jockey Club release based on information collected in the Equine Injury Database, fatal injuries in North American Thoroughbred races stayed about the same in 2012 at just under two per 1,000 starts.